Phospholipid composition of high-density lipoproteins reflects lipolysis of triglyceride-rich lipoproteins during hyperlipidemia

Autor:	N V, Perova, I N, Ozerova, I V, Paramonova, A M, Olfer'ev, N M, Akhmedzhanov, L I, Pavlova, R G, Oganov
Rok vydání:	2000
Předmět:	Adult Male Simvastatin Cardiolipins Anticholesteremic Agents Lipolysis Phosphatidylethanolamines Cholesterol HDL Lysophosphatidylcholines Hyperlipidemias Middle Aged Sphingomyelins Cholesterol Fenofibrate Phosphatidylcholines Humans Lipoproteins HDL Phospholipids Triglycerides Hypolipidemic Agents
Zdroj:	Bulletin of experimental biology and medicine. 131(4)
ISSN:	0007-4888
Popis:	We studied phospholipid composition of high-density lipoproteins in patients with normo- and hypertriglyceridemia treated with various hypolipidemic preparations (simvastatin and fenofibrate). Both preparations changed phospholipid composition of high-density lipoproteins and improved their functional activity. The differences in the phospholipid composition of high-density lipoproteins were probably related to lipolysis of triglyceride-rich lipoproteins catalyzed by lipoprotein lipase and, in particular, hepatic lipase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::25ed9b4bbc122e40b77f08bdc9a7988e https://pubmed.ncbi.nlm.nih.gov/11550015 Zobrazit plný text záznamu Full text from SpringerLink