| Autor: |
Harishini, Rajaratinam, Nur Syahmina, Rasudin, Sabreena, Safuan, Nurul Asma, Abdullah, Noor Fatmawati, Mokhtar, Wan Ezumi, Mohd Fuad |
| Rok vydání: |
2021 |
| Zdroj: |
The Malaysian journal of medical sciences : MJMS. 29(3) |
| ISSN: |
1394-195X |
| Popis: |
The study was aimed to elucidate the influence of passage number of 4T1 cells for the development of the ideal tumour model.A total of 24 female BALB/c mice was divided equally into three groups: i) control (phosphate buffered saline [PBS] only); ii) group A (subjected to 4T1 cells of passage number 9) and iii) group B (subjected to 4T1 cells of passage number 10). The injections were introduced at the 3rd mammary pad of the mice. The net volume of the tumours was examined. Histopathological analysis was conducted to compare the extent of metastasis in the different groups of mice.Group B had a higher net volume of 4T1 tumour as compared to group A (The use of 4T1 cells from passage number 10 is more ideal for the development of 4T1 tumour. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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