Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women
| Autor: | R, Hamkar, S, Jalilvand, M H, Abdolbaghi, K N, Jelyani, A, Esteghamati, A, Hagh-goo, T, Mohktari-Azad, R, Nategh |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Chi-Square Distribution Adolescent Medical Errors Antibody Affinity Iran Antibodies Viral Mass Vaccination Statistics Nonparametric Immunoenzyme Techniques Predictive Value of Tests Pregnancy Seroepidemiologic Studies Immunoglobulin G Humans Female Rubella Vaccine Pregnancy Complications Infectious Rubella virus Rubella |
| Zdroj: | Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit. 15(1) |
| ISSN: | 1020-3397 |
| Popis: | During the mass measles/rubella vaccination campaign in 2003 in Iran, many pregnant women were vaccinated mistakenly or became pregnant within 1 month of vaccination. To distinguish pregnant women who were affected by rubella vaccine as primary infection from those who had rubella reinfection from the vaccine, serum samples were collected 1-3 months after the campaign from 812 pregnant women. IgG avidity assay showed that 0.3% of the women had no rubella-specific IgG response; 14.4% had low-avidity anti-rubella IgG and were therefore not immune to rubella before vaccination; 85.3% had high-avidity anti-rubella IgG and were regarded as cases of reinfection. |
| Databáze: | OpenAIRE |
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