| Autor: |
A V, Pugach, V V, Zverev, E R, Pille, N R, Shukhmina, N L, Mel'nikova, D N, Nosik, V V, Maliushova, O G, Andzhaparidze |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Voprosy virusologii. 38(6) |
| ISSN: |
0507-4088 |
| Popis: |
Ten hybridomas secreting monoclonal antibodies (Mab) against recombinant HIV-1 and HIV-2 antigens were produced (3 Mab anti-gag protein, 2 anti-env1, and 5 anti-env2). In the immunoblotting assay all the anti-gag Mabs reacted with HIV capsid protein p24, whereas one of them reacted also with p55 protein and with 7 other polypeptides. Another anti-gag Mab cross-reacted with the antigen of subpopulation of human peripheral blood lymphocytes. The third one interacted with the antigen of both HIV-1 and HIV-2. All the 10 Mabs interacted with natural HIV antigens and can be used for identification and differentiation of HIV-1 and HIV-2. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
