Dipeptides delay the onset of morphine withdrawal in the mouse

Autor:	G L, Kovács, L, Szontágh, L, Baláspiri, G, Telegdy
Rok vydání:	1984
Předmět:	Male Analysis of Variance Mice Morphine Naloxone Animals Humans Dipeptides Morphine Dependence Pyrrolidonecarboxylic Acid Substance Withdrawal Syndrome
Zdroj:	Acta physiologica Hungarica. 63(1)
ISSN:	0231-424X
Popis:	The effect of dipeptides was studied on naloxone-precipitated morphine withdrawal in the mouse. In accordance with previous data, s.c. treatment with Z-prolyl-D-leucine delayed the onset of withdrawal jumpings . Replacement of L-proline by L-glutamate or L-pyroglutamate resulted in dipeptides which were more potent in morphine withdrawal than was Z-prolyl-D-leucine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2569b8f720c12242045dc9ef07311a29 https://pubmed.ncbi.nlm.nih.gov/6540034 Zobrazit plný text záznamu