[Effects of complexes of alpha-fetoprotein and amphiphilic docosaenoic acid derivatives on the humoral immune response in C57BL/6 mice]

Autor: D V, Arsenov, M B, Golubeva, M A, Kisel', N A, Konoplia, B B, Kuz'mitskiĭ, G S, Liubin, O A, Strel'chenok
Rok vydání: 2002
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia. 65(3)
ISSN: 0869-2092
Popis: The immunotropic activity of three derivatives of docosahexaenic acid (N-docosahexaenoyl-L-serine phosphate, N-docosahexaenoyl-L-threonine phosphate, and N-docosahexaenoyl-L-tyrosine phosphate) in complexes with high-purity human alpha-fetoprotein was evaluated. The polyene compounds stimulate the humoral immunity in mice immunized with T-dependent antigen (ram red blood cells). The immunotropic activity of the alpha-fetoprotein-ligand complexes studied depends on the structure and the content of polyene ligands.
Databáze: OpenAIRE