Nosocomial transmission of an avian-like rotavirus strain among children in Belém, Brazil

Autor: R H, Gusmão, J D, Mascarenhas, Y B, Gabbay, A C, Linhares
Rok vydání: 1994
Předmět:
Zdroj: Journal of diarrhoeal diseases research. 12(2)
ISSN: 0253-8768
Popis: An atypical group-A rotavirus strain, with an electrophoretype displaying 5 segments in the first dsRNA size class, was detected among 3 hospitalized children less than 2 years old. Detection occurred initially 24 h after admission in a non-diarrhoeic child hospitalized because of acute respiratory infection. The second detection involved a child who occupied a different room within the same ward and who developed nosocomial diarrhoea 48 h later. A third case, also of hospital-acquired diarrhoea, was recorded in a child who occupied a bed in the same room as the second case and developed gastroenteritis 24 h following the second case's detection. In addition to the unusual, avian-like genomic profile, the strain was classified as serotype 2, based on a human VP7-specific enzyme-linked immunosorbent assay (ELISA). The question of whether these events reflect either a genomic rearrangement of a human rotavirus strain or a possible interspecies transmission will be further investigated through hybridization assays.
Databáze: OpenAIRE