| Autor: |
Chao, Cheng, Ye-Xin, Lin, Jiu-Jun, Li, Zhi-Jie, Zhang |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. 17(9) |
| ISSN: |
1008-8830 |
| Popis: |
To explore the risk factors for sepsis caused by multidrug-resistant Klebsiella pneumonia (MDR-KP) and to provide a reference for the prevention of MDR-KP sepsis and rational use of antibiotics.A retrospective case-control study of 41 children with MDR-KP sepsis (case group) and 53 pediatric patients without MDR-KP sepsis (control group) between March 2010 and Febrary 2014 was conducted. Multiple logistic regression analysis was performed to estimate the independent risk factors for MDR-KP sepsis.Compared with the control group, the case group had a longer length of stay in the PICU before infection (P0.05), more prolonged duration of mechanical ventilation before infection (P0.05), a larger total number of days of mechanical ventilation (P0.05), more days of antibiotic use before infection (P0.05), more types of antibiotics used before infection (P0.05), and a higher mortality (P0.05). The logistic regression analysis showed that more types of antibiotics used before infection and use of third-generation cephalosporin and carbapenems were independent risk factors for MDR-KP sepsis (P0.05).Rational use of antibiotics is an effective measure to prevent MDR-KP sepsis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
