| Autor: |
Selvam, Karthik, Arunachalam, Thirugnanasambandam, Pradeep Kumar, Mandal, Namasivayam, Gautham |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Acta crystallographica. Section F, Structural biology communications. 73(Pt 5) |
| ISSN: |
2053-230X |
| Popis: |
The X-ray crystal structure of the DNA tetradecamer sequence d(CCGGGGTACCCCGG)(2) is reported at 1.4 Å resolution in the tetragonal space group P4(1)2(1)2. The sequence was designed to fold as a four-way junction. However, it forms an A-type double helix in the presence of barium chloride. The metal ion could not be identified in the electron-density map. The crystallographic asymmetric unit consists of one A-type double helix with 12 base pairs per turn, in contrast to 11 base pairs per turn for canonical A-DNA. A large number of solvent molecules have been identified in both the grooves of the duplex and around the backbone phosphate groups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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