Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease

Autor:	R S, Gilgor, A, Chiaramonti, L A, Goldsmith, G S, Lazarus
Rok vydání:	1980
Předmět:	Adult Male Adolescent Dose-Response Relationship Drug Ichthyosis Tretinoin Middle Aged Conjunctivitis Cheilitis Evaluation Studies as Topic Pityriasis Rubra Pilaris Humans Female Child Isotretinoin Darier Disease
Zdroj:	Cutis. 25(4)
ISSN:	0011-4162
Popis:	A new synthetic oral retinoid, 13-cis retinoic acid, is fairly well tolerated in patients and appears to be effective in those with Darier's disease and lamellar ichthyosis. It is less effective in those with pityriasis rubra pilaris. The mechanism of action of 13-cis retinoic acid in disorders of keratinization is unknown at the present time; however, it does not appear to cause lysosomal proliferation in therapeutic doses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::24dc240f4d3527764345bc94c3893873 https://pubmed.ncbi.nlm.nih.gov/6928816 Zobrazit plný text záznamu