| Autor: |
Claudine, Bommer, Tobias, Waller, Monika, Hilbe, Daniel, Wiedemeier, Nina, Meyer, Stephanie, Mathes, Ronald, Jung |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Clinical oral investigations. 26(3) |
| ISSN: |
1436-3771 |
| Popis: |
This study's aim was to investigate the safety and performance of a self-assembling peptide matrix (SAPM) PAcute buccal bony dehiscence defects (LxW: 5 × 3 mm) were surgically created on the distal root of four teeth on one mandible side of 7 beagle dogs followed by another identical surgery 8 weeks later on the contralateral side. SAPM PClinically and histologically, no safety concerns or pathological issues due to the treatments were observed in any of the study groups at any time point. All groups showed overall similar results after 4 and 12 weeks of healing regarding new cementum, functionality of newly formed periodontal ligament and recovery of height and volume of the new alveolar bone and mineral density.A controlled clinical study in humans should be performed in a next step as no adverse effects or safety issues, which might affect clinical usage of the product, were observed.The synthetic SAPM P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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