Efferocytosis requires periphagosomal Ca

Autor: Michael S, Schappe, Marta E, Stremska, Gregory W, Busey, Taylor K, Downs, Philip V, Seegren, Suresh K, Mendu, Zachary, Flegal, Catherine A, Doyle, Eric J, Stipes, Bimal N, Desai
Rok vydání: 2019
Předmět:
Zdroj: Nature communications. 13(1)
ISSN: 2041-1723
Popis: Efficient clearance of apoptotic cells by phagocytosis, also known as efferocytosis, is fundamental to developmental biology, organ physiology, and immunology. Macrophages use multiple mechanisms to detect and engulf apoptotic cells, but the signaling pathways that regulate the digestion of the apoptotic cell cargo, such as the dynamic Ca
Databáze: OpenAIRE