| Autor: |
H A, Babiker, L C, Ranford-Cartwright, D, Walliker |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
Transactions of the Royal Society of Tropical Medicine and Hygiene. 93 |
| ISSN: |
0035-9203 |
| Popis: |
Plasmodium falciparum parasites exist as genetically distinct haploid clones in infected people. In the Kilombero valley in south-east Tanzania, at least 85% of the inhabitants of Michenga village harbour more than one clone. Using 2 highly polymorphic unlinked markers, it has been estimated that each infected person harbours between one and 6 P. falciparum clones at any one time, with a mean of 3.5 clones. When mosquitoes acquire gametocytes of 2 different clones in a blood meal, crossing generates recombinant clones differing from their parental genotypes. The inbreeding coefficient of the parasite population has been estimated as 0.33. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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