| Autor: |
Xuyi, Wang, Xuhui, Zhou, Yanhui, Liao, Jinsong, Tang, Tieqiao, Liu, Wei, Hao |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 36(8) |
| ISSN: |
1672-7347 |
| Popis: |
To explore what brain regions are modulated by heroin addiction and withdrawal.We used functional magnetic resonance imaging to investigate the brain function in 15 heroin-dependent patients 3 days (acute) and 1 month (protracted) after heroin abstinence. Sixteen normal controls were included.The blood oxygen level-dependent signal in the orbitofrontal cortex of the brain of heroin-dependent patients was significantly elevated 3 days after the withdrawal. Hyperfunction of the orbitofrontal cortex declined 1 month after the withdrawal.Heroin-dependent subjects at both 3 days and 1 month abstinence have persistent abnormalities in the brain function. Although some tangible beneficial effects are noted following 1 month of detoxification, possible permanent damage to the brain caused by heroin use is suggested. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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