Levamisole treatment in ulcus cruris. A double-blind placebo-controlled study

Autor: J, Morias, W, Peremans, H, Campaert, R L, Mertens
Rok vydání: 1979
Předmět:
Zdroj: Arzneimittel-Forschung. 29(7)
ISSN: 0004-4172
Popis: 59 outpatients (27-82 years) with a chronic leg ulcer participated in a 20-week double-blind placebo-controlled trial of levamisole (levamisole 30; placebo 29). They were instructed to take a body weight adjusted number of tablets (2-5) for two consecutive days every week. Previously used topical treatment was kept unchanged. Control examinations were done every two weeks. Double-blind treatment was stopped because of evident failure after a median duration of 8 weeks in 2 levamisole and 8 placebo patients. The percentage of cured patients became significantly superior in the levamisole group from week 8 onwards, so that, by the end of the study, all levamisole patients were cured against only 76% of the controls. Three levamisole patients reported moderate gastric complaints.
Databáze: OpenAIRE