Comparison of efficacy between continuous hemodiafiltration with a PMMA high-performance membrane dialyzer and a PAN membrane hemofilter in the treatment of septic shock patients with acute renal failure
| Autor: | Kenichi, Matsuda, Takeshi, Moriguchi, Norikazu, Harii, Masahiko, Yanagisawa, Daiki, Harada, Hisanori, Sugawara |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Acrylic Resins Membranes Artificial Hemodiafiltration Acute Kidney Injury Middle Aged Combined Modality Therapy Severity of Illness Index Shock Septic Survival Rate Treatment Outcome Body Water Furosemide Fluid Therapy Humans Polymethyl Methacrylate Female Adsorption Hemofiltration Hypotension Inflammation Mediators Diuretics Aged |
| Zdroj: | Contributions to nephrology. 173 |
| ISSN: | 1662-2782 |
| Popis: | The aim of this study was to investigate whether continuous hemodiafiltration (CHDF) with a high-performance membrane dialyzer made of polymethylmethacrylate (PMMA-CHDF) in the treatment of septic shock patients with acute renal failure (ARF) is clinically relevant. 30 patients were treated with PMMA-CHDF. 13 patients treated with CHDF used a hemofilter made of polyacrylonitrile membrane (PAN-CHDF). Systolic blood pressure significantly increased in the PMMA-CHDF group following 24 h of treatment (p0.01), whereas it did not improve in the PAN-CHDF group. Urine volume significantly increased in the PMMA-CHDF group following 24 h of treatment which was more than in the PAN-CHDF group (p0.05). 28-day survival was 83.3% in the PMMA-CHDF group and 30.8% in the PAN-CHDF group, respectively (p0.01). We can assume that PMMA-CHDF in the treatment of septic shock patients with ARF is clinically relevant. |
| Databáze: | OpenAIRE |
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