| Autor: |
A, Frank-Piskorska, T, Płusa, E, Józefczak, M, Kałczak |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
Pneumonologia i alergologia polska. 61(7-8) |
| ISSN: |
0867-7077 |
| Popis: |
The aim of the study was to analyse the clinical effectiveness of ofloxacin in treatment of post-infectious exacerbations of endogenous bronchial asthma. Twenty eight patients (20 males, 8 females) were assessed. The following parameters were evaluated: bacteriological examination of the sputum (before and after treatment), morphological analysis of peripheral blood, bronchoalveolar lavage (performed in 11 patients). Additionally in 7 patients lymphocyte subpopulations of the peripheral blood were determined (OKT4/OKT8). Diurnal variations of serum levels of theophylline were assessed in 12 patients. The authors observed a clinical improvement in 26 patients. Following treatment the white cell blood count (WBC) and the CD4/CD8 ratio decreased. The same observations were made analysing the BAL differential count, in which a marked decrease of neutrophils was seen. The authors conclude that ofloxacin is a safe and efficient antimicrobial agent. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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