[Immunogenic properties of virus-specific soluble structural glycoproteins synthesized by chick embryo fibroblast cells infected with 2 strains of Aujeszky's disease virus]

Autor:	V, Khristova
Rok vydání:	1987
Předmět:	Viral Structural Proteins Virus Cultivation Virulence Virion Chick Embryo Fibroblasts Antibodies Viral Herpesvirus 1 Suid Viral Proteins Solubility Antibody Specificity Mutation Animals Rabbits Glycoproteins
Zdroj:	Veterinarno-meditsinski nauki. 24(7)
ISSN:	0324-1068
Popis:	Studied was the capacity of the soluble virus-specific glycoproteins of the virulent A-2 strain and its IUDR-resistant MK-25 mutant to induce the production of virus-neutralizing antibodies. It was found that both the purified virions and soluble glycoproteins of strain A-2 and those of strain MK-25 induced the release of virus-neutralizing antibodies in the injected rabbits. Use was made of affinity chromatography on Con-A-Sepharose to isolate the glycosylated virus-specific proteins. The quality of the soluble virus-specific glycoproteins to trigger the production of virus-neutralizing antibodies made it reasonable to believe that the virus glycoproteins are structural ones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2415884b130775332c30f8a135e1ba94 https://pubmed.ncbi.nlm.nih.gov/2823455 Zobrazit plný text záznamu