[Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders]

Autor: V P, Batmanov
Rok vydání: 1991
Předmět:
Zdroj: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 36(9)
ISSN: 0235-2990
Popis: Thirteen strains of P. mallei were found to be highly sensitive to ciprofloxacin and ofloxacin and resistant to norfloxacin. Ciprofloxacin and ofloxacin showed a high efficacy on models of malleus in guinea pigs and hamsters. The animals were infected with various strains of P. mallei. In the in vitro experiments, ciprofloxacin proved to be the most active and efficient. Norfloxacin appeared to be inefficient.
Databáze: OpenAIRE