| Autor: |
R E, Thompson, C R, Hewitt, D J, Piper, W P, Hansen, R H, Rubin, N E, Tolkoff-Rubin, M C, Barrett, M J, Nelles |
| Rok vydání: |
1985 |
| Předmět: |
|
| Zdroj: |
Clinical chemistry. 31(11) |
| ISSN: |
0009-9147 |
| Popis: |
This competitive immunoassay, based on inhibition by antigen of the idiotype-anti-idiotype interaction, detects adenosine deaminase binding protein (ABP), and involves use of monoclonal anti-idiotype antibodies prepared to a monoclonal antibody specific for ABP. The conditions for this new type of competitive immunoassay are investigated. This competitive immunoassay is as sensitive and reproducible as an earlier described "sandwich"-type immunoassay for ABP (Clin Chem 31: 679-683, 1985). Evaluation of urine samples from normal subjects and from patients showed increased concentrations of ABP in patients with renal disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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