| Autor: |
Mario, García-Carrasco, Claudia, Mendoza-Pinto, Jorge, Ayón-Aguilar, Pamela, Soto-Santillán, Alma, Rodríguez-Gallegos, Marco Antonio, Escamilla-Márquez, Socorro, Méndez-Martínez |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Gaceta medica de Mexico. 152(Suppl 2) |
| ISSN: |
0016-3813 |
| Popis: |
To determine changes over time of serum levels of 25-hydroxy vitamin D (25(OH)D) in Mexican patients with SLE and their relationship with disease activity.Longitudinal and observational study. Women with SLE were included. Serum levels of 25(OH)D were measured at baseline and after two years; the disease activity was measured with MEX-SLEDAI. Patients with initial suboptimal levels of 25(OH)D received supplements or increased doses of calcitriol.105 women with SLE were included, mean age 49.4 ± 11 years. Serum levels of 25(OH)D were higher at two years (baseline 20 ± 6.8 vs. follow-up 22.7 ± 7.7; p =0.001). There were no differences between disease activity scores at baseline and two years (baseline 1.7 ± 1.9 vs. follow-up 1.1 ± 1.7; p = 0.7). Serum levels of 25(OH)D did not correlate with disease activity during the follow up, p = 0.7. No correlation was found between changes in MEX-SLEDAI scores and serum levels of 25(OH)D, p = 0.87.Mexican women with SLE had increased serum levels of 25(OH)D. No correlation between serum levels of 25(OH)D and disease activity was found. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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