| Autor: |
T, Fukuoka, Y, Yamamoto, E, Usami, H, Hayashi, J, Utsunomiya, M, Kimura, M, Nakamura, T, Yoshimura, Y, Toda |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Die Pharmazie. 77(5) |
| ISSN: |
0031-7144 |
| Popis: |
Vincristine (VCR) is an important drug used in R-CHOP regimens for the treatment of non-Hodgkin's lymphoma. The purpose of this study was to examine whether the administration method affects the incidence of VCR-induced peripheral neuropathy. We investigated the ratio of VCR-induced peripheral neuropathy during rapid intravenous infusion and intravenous drip infusion. A total of 71 patients who had received six or more courses of R-CHOP from January, 2015 to December, 2016 at Komaki City Hospital and Ogaki Municipal Hospital were retrospectively investigated. Peripheral neuropathy was observed in 27/39 patients (69 %) and 24/32 (75 %) in rapid intravenous infusion and intravenous drip infusion of VCR, respectively ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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