| Autor: |
Ali, Al-Asmari, Abdul Ali, Peer-Zada, Abdulwahed, AlDehaimi, Constantin, Polychronakos, Aziz A, Chentoufi |
| Rok vydání: |
2021 |
| Zdroj: |
Saudi journal of biological sciences. 29(12) |
| ISSN: |
1319-562X |
| Popis: |
The aim of this study is to develop a rapid and effective method to screen for Saudi carriers of one of the most common propionic acidemia mutations (c.425G A) and to study the functional impact of this mutation. Using allele-specific primers, we have developed a qPCR assay that clearly distinguishes heterozygotes from mutated and wild type homozygotes that overcome the dependence on labor-intensive gene sequencing. We show here that ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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