New drug controls and reduced hospital presentations due to novel psychoactive substances in Edinburgh

Autor:	Janice, Pettie, Allan, Burt, Duleeka W, Knipe, Hazel, Torrance, Margaret, Dow, Karen, Osinski, Robert, Greig, Diletta, Sabatini, Kate, Easterford, James, Dear, Michael, Eddleston
Rok vydání:	2017
Předmět:	Adult Male Psychotropic Drugs Illicit Drugs Thiophenes Original Articles Methamphetamine Hospitalization Young Adult Scotland Methylphenidate Drug and Narcotic Control Humans Central Nervous System Stimulants Female Substance Abuse Oral Hospital Costs Program Evaluation
Zdroj:	British journal of clinical pharmacology. 84(10)
ISSN:	1365-2125
Popis:	AIMS: Recreational use of novel psychoactive substance (NPS) has become increasingly common. We aimed to assess the association of national legislation and local trading standards activity with hospital presentations. METHODS: We established observational cohorts of patients with recreational drug toxicity presenting to Edinburgh Royal Infirmary and dying with detectable recreational drugs in Edinburgh. We assessed associations with two temporary class drug‐orders (April 2015: methylphenidates, Nov 2015: methiopropamine), the Psychoactive Substances Act (June 2016), and trading standards forfeiture orders (October 2015). RESULTS: The methylphenidate temporary class drug‐order was associated with rapid 46.7% (P = 0.002) and 21.0% (P = 0.003) reductions in presentations and admissions, respectively, for NPS drug toxicity, comparing 12 months before with 6 months after. The change was greatest for ethylphenidate toxicity (96.7% reduction in admissions, P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2383a345c194f01b9ff224b6de112c29 https://pubmed.ncbi.nlm.nih.gov/29911343 Zobrazit plný text záznamu Plný text