| Autor: |
A P, Warin, J W, Landells, G M, Levene, H, Baker |
| Rok vydání: |
1975 |
| Předmět: |
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| Zdroj: |
The British journal of dermatology. 93(3) |
| ISSN: |
0007-0963 |
| Popis: |
The results are reported of a prospective study of liver histological findings in twenty-five patients with severe psoriasis subjected to liver biopsy before and at intervals after the onset of treatment with methotrexate by an intermittent dosage schedule. The pre-methotrexate liver biopsy findings in forty-one other severe psoriatics are also summarized. Of the twenty-five treated patients, four showed a mild inflammatory cell infiltrate and two mild fibrosis before treatment. During treatment only one developed a grade 2 infiltrate and one other grade 2 fibrosis. None has developed cirrhosis. Where minor abnormalities developed, their fluctuating and reversible nature is demonstrated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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