[A cytomorphological basis for the correction of radiation-induced immunodeficiencies and hematopoietic depression using thymus and bone marrow peptides]
| Autor: | O K, Khmel'nitskiĭ, I I, Grintsevich, V A, Kotov, S V, Seryĭ |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Adolescent Guinea Pigs Drug Evaluation Preclinical Immunologic Deficiency Syndromes Middle Aged Hematopoiesis Thymus Hormones Drug Combinations Radiation Injuries Experimental Adjuvants Immunologic Animals Drug Evaluation Humans Intercellular Signaling Peptides and Proteins Female Peptides Radiation Injuries Radioactive Hazard Release Ukraine Power Plants |
| Zdroj: | Arkhiv patologii. 55(2) |
| ISSN: | 0004-1955 |
| Popis: | The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied. Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes. Thymalin was able to compensate for immune disturbances and reduce manifestations of asthenia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|