| Autor: |
C C, Musatti, K, Yasaka, L M, Santos |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 20(3-4) |
| ISSN: |
0100-879X |
| Popis: |
1. The proliferative response of phytohemagglutinin-activated lymphocytes from patients with Hodgkin's and non-Hodgkin's lymphoma was compared to their interleukin-2 (IL-2) production. 2. Impairment in the lymphoproliferative response paralleled a reduction in IL-2 production. 3. Suppressor cells and serum factors which depressed the proliferative response of the patients' lymphocytes inhibited IL-2 production. 4. Enhanced prostaglandin synthesis was one of the factors causing impairment of the proliferative response and the diminished IL-2 production in lymphocytes from patients with lymphoma. 5. A partial restoration of patients' cellular responses in vitro was achieved by adding conditioned media containing IL-1 or IL-2. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
