[Endonucleolysis of chromatin in thymocytes of irradiated and non-irradiated rats]
Autor: | B P, Ivannik, R V, Sin'kova, A V, Konov, N I, Riabchenko |
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Rok vydání: | 1986 |
Předmět: | |
Zdroj: | Radiobiologiia. 26(2) |
ISSN: | 0033-8192 |
Popis: | It was shown that in conditions optimal for Ca/Mg endonuclease, chromatin endonucleolysis in the nuclei and thymocytes occurs due to internucleosome fragmentation of DNA. Irradiation activates chromatin degradation in thymocytes washed by a buffer containing 0.25 M sucrose, 10 mM tris-HCl, pH 7.2, 3 mM MgCl2, and does not influence this process in thymocytes washed by 10 mM tris-HCl, pH 7.2, 3 mM MgCl2. |
Databáze: | OpenAIRE |
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