Autor: |
Shu-Peng, Zhao, Ying-Hua, Ji, Qing-Kai, Guan, Ji-Wei, Ma, Cai-Ling, Jin, Xiang-Yang, Wang, Xin-Li, Zhao |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 51(5) |
ISSN: |
1672-173X |
Popis: |
To investigate the effect of overexpression of miR-382-5p overexpression on malignant biological behavior of human glioma U251 cells.U251 cells were transfected with miR-382-5pmimic. Then miR-382-5p andResults showed that miR-382-5p directly targeted PTEN. Compared with the control group, miR-382-5p andOverexpression of miR-382-5p mediates the downregulation of PTEN expression, causing the inhibition of the proliferation, invasion, growth and EMT of U251 glioma cells. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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