| Autor: |
G M, Cohn, R C, Miller, M, Gould, C J, Macri, M L, Gimovsky |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
The Journal of reproductive medicine. 44(1) |
| ISSN: |
0024-7758 |
| Popis: |
To evaluate the utility of the prenatal three-generation pedigree in assessment of the obstetric patient's primary medical risks.In a case series, 250 charts of patients referred for amniocentesis on the basis of advanced maternal age were reviewed for a significant genetic risk of a primary care disorder.A total of 40 patients (16%) were at significantly increased risk for a primary care disorder. Thirty-eight patients (15.2%) were at increased risk for medical conditions for which early screening, detection and/or intervention are established.For the advanced maternal age population, formal genetic risk assessment performed prior to amniocentesis can be beneficial in primary care risk assessment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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