Comparison of bioimpedance and radioisotope methods in the estimation of extracellular water volume before and after coronary artery bypass grafting operation

Autor: T, Kööbi, M, Kähönen, M, Koskinen, S, Kaukinen, V M, Turjanmaa
Rok vydání: 2000
Předmět:
Zdroj: Clinical physiology (Oxford, England). 20(4)
ISSN: 0144-5979
Popis: To estimate extracellular water volume (ECW) changes in connection with coronary artery bypass grafting operation, simultaneous ECW estimations by 51Cr-EDTA dilution and whole-body bioimpedance techniques were performed in 15 patients. The assessments of ECW were compared with patients' weighing results. Whole-body bioimpedance-derived ECW correlated significantly with 51Cr-EDTA dilution-based ECW in the pre-operative period (r=0.74; P0.005); the bias was 0.2 +/- 1.1 l (+/-SD). In the post-operative period, the agreement between these methods was poor, the bias being 0.5 +/- 2.5 l, and no significant correlation between the methods was found (r=0.38; P0.05). Whole-body bioimpedance-derived ECW changes correlated significantly with weight changes of the patient induced by the operation (r=0.52; P0.05). 51Cr-EDTA dilution-based ECW changes correlated neither with weight changes (r=0.33; P0.05) nor with bioimpedance-derived ECW changes (r=0.03; P0.05). Alterations in radioisotope tracer distribution and loss of it due to blood leakage in the post-operative period were presumed to explain the discrepancy between dilution technique and weighing results. The results suggest that bioimpedance is a useful non-invasive method for assessment of extracellular volume changes induced by coronary artery bypass grafting operations. 51Cr-EDTA dilution-based ECW determination is not suitable in related conditions.
Databáze: OpenAIRE