[Excitation of the hydrogen bond by the energy of hydrolysis of adenosine-5'-triphosphate]

Autor: S V, Bespalova, K B, Tolpygo
Rok vydání: 1998
Předmět:
Zdroj: Biofizika. 43(3)
ISSN: 0006-3029
Popis: The model of muscle contraction suggested in [1] is based on the hypothesis that the first step of the conversion of chemical energy delta E (which is stored in adenosine-5'-triphosphate) is the excitation of the hydrogen bond in the actin-myosin system with a simultaneous hydrolysis of the adenosine-5'-triphosphate molecule. As a consequence, the potential barrier is decreased, and the break of the macroergic bond adenosine-5'-triphosphate-phosphate is facilitated. With the delta E value exceeding the excitation energy of the H-bond, this process represents an exothermic reaction. A simple model of this process is constructed, and its probability depending on temperature and the mutual position of the H-bond and the adenosine-5'-triphosphate molecule is estimated.
Databáze: OpenAIRE