Quantitative determination of immunological components of salivary gland secretion in transplant recipients

Autor: F, Dens, M, Boogaerts, P, Boute, D, Declerck, H, Demuynck, F, Vinckier
Rok vydání: 1996
Předmět:
Zdroj: Bone marrow transplantation. 17(3)
ISSN: 0268-3369
Popis: Cancer therapies often induce oral complications. We studied longitudinally the major salivary immunoglobulin content in 42 transplant recipients using an enzyme-linked immunosorbent assay. A dramatic decrease in both sIgA and IgG is noticed post-transplant compared to pretransplant values. Only a small recovery of these immunoglobulin concentrations is seen after approximately 4 months. The reduction of sIgA and IgG in saliva could contribute to the frequent oral complications seen in these patients after transplantation and increase the risk of developing dental caries.
Databáze: OpenAIRE