| Autor: |
O O, Moĭbenko, V F, Sahach, M M, Tkachenko, O V, Korkushko, V V, Bezrukov, O K, Kul'chyts'kyĭ, O V, Stefanov, A I, Solovĭov, L T, Mala, V V, Frol'kis |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 50(1) |
| ISSN: |
2522-9028 |
| Popis: |
General characteristics and mechanisms of effects of nitric oxide (NO) and its role in the development of pathology are reviewed. Presented are the data about NO participation in the regulation of circulation and cardiovascular system; NO-dependent mechanism of regulation of cardiovascular reactivity against the background of dysfunction of endothelium; cGMP-independent mechanism of NO effect upon Ca homeostasis and the sensitivity of myofibrils of smooth muscle cells to Ca ions; pharmacological correction of disturbances of NO metabolism and related endothelial dysfunction; role of age changes of the endothelial function in the development of cardiovascular pathology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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