Decreased susceptibility to imipenem among penicillin-resistant Streptococcus pneumoniae

Autor: A, Pikis, J A, Donkersloot, S, Akram, J M, Keith, J M, Campos, W J, Rodriguez
Rok vydání: 1997
Předmět:
Zdroj: The Journal of antimicrobial chemotherapy. 40(1)
ISSN: 0305-7453
Popis: We assessed the antimicrobial susceptibilities of 59 penicillin-intermediate or penicillin-resistant pneumococci. All strains were susceptible to vancomycin and rifampicin. The frequency of strains with decreased susceptibility to cefotaxime, chloramphenicol, imipenem and meropenem was 15, 31, 47 and 49% respectively. The high percentage of penicillin-intermediate or penicillin-resistant Streptococcus pneumoniae with decreased susceptibility to third-generation cephalosporins, chloramphenicol and carbapenems limits the therapeutic options for the treatment of invasive pneumococcal infections and particularly of meningitis.
Databáze: OpenAIRE