| Autor: |
W, Arcese, A P, Iori, M, Screnci, C, Guglielmi, A, Mengarelli, D, Carmini, A M, Testi, M L, Moleti, G, Cimino, P, Perrone, L, Laurenti, L, Elia, F, Boecklin, A, Romano, L, De Felice, F, Mandelli |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Bone marrow transplantation. 21 |
| ISSN: |
0268-3369 |
| Popis: |
Twelve consecutive children with high-risk leukemia have been submitted to UCB transplant from unrelated 1 or 2 loci HLA-mismatched donor. All patients received an identical regimen for conditioning and GVHD prophylaxis. The median dose of viable nucleated cells infused was 2.8 x 10(7)/kg bw (range 1.4-7.9). Of 11 patients evaluable for engraftment, the hematopoiesis was of full donor origin in seven patients and autologous in four. The probability of disease-free survival at 1 and 2 years from UCB transplant is 60 and 42%, respectively. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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