| Autor: |
Camilo, Pena, Leonardo, Mirandola, Jose A, Figueroa, Nattamol, Hosiriluck, Natallia, Suvorava, Kayley, Trotter, Adair, Reidy, Rahman, Rakhshanda, Drew, Payne, Marjorie, Jenkins, Fabio, Grizzi, Lauren, Littlefield, Maurizio, Chiriva-Internati, Everardo, Cobos |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Annals of translational medicine. 2(9) |
| ISSN: |
2305-5839 |
| Popis: |
Galectins are family of galactose-binding proteins known to play critical roles in inflammation and neoplastic progression. Galectins facilitate the growth and survival of neoplastic cells by regulating their cross-talk with the extracellular microenvironment and hampering anti-neoplastic immunity. Here, we review the role of galectins in the biology of hematological malignancies and their promise as potential therapeutic agents in these diseases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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