| Autor: |
J V, Rojo, L O, González, M L, Lamelas, A, Merino, F, Vizoso |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
Acta obstetricia et gynecologica Scandinavica. 80(2) |
| ISSN: |
0001-6349 |
| Popis: |
Apolipoprotein D is a protein component of the human plasma lipid transport system but is also associated with a more favorable prognosis in breast cancer and ovarian cancer women. This study was undertaken to examine the tumoral expression of apolipoprotein D in endometrial cancer and to analyze the possible correlation with tumor and patients characteristics as well as androgen receptors and its prognostic significance.Immunohistochemical evaluation was used to examine apolipoprotein D expression in paraffin blocks from 58 endometrial carcinomas.A total of twenty (34%) tumors stained positively. Staining was localized in tumor cells. No significant correlation was found between apo D expression and patients or tumor characteristics and androgen receptor status. In addition, apolipoprotein D expression was not associated with patient prognosis.Apolipoprotein D is expressed by a significant percentage of endometrial carcinomas without apparent association with other clinicopathologic parameters or with outcome of patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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