Radiotherapy of Prostate Carcinoma: A Comparison of the Predictive Role of EAU

Autor:	Milly, Buwenge, Francesco, Deodato, Naama, Dominsky, Maria, Ntreta, Savino, Cilla, Giambattista, Siepe, Anna Rita, Alitto, Silvia, Bisello, Vincenzo, Valentini, Gabriella, Macchia, Alessio G, Morganti
Rok vydání:	2020
Předmět:	Male Salvage Therapy Prostatic Neoplasms Radiotherapy Dosage Prostate-Specific Antigen Risk Assessment Survival Analysis Observational Studies as Topic Treatment Outcome Humans Multicenter Studies as Topic Kallikreins Radiotherapy Adjuvant Aged Retrospective Studies
Zdroj:	Anticancer research. 40(8)
ISSN:	1791-7530
Popis:	To compare the predictive efficacy of National Comprehensive Cancer Network (NCCN) and European Association of Urology (EAU) risk stratification systems in radiotherapy of prostate cancer.One-thousand-nine-hundred-nine patients treated with definitive (1,074), adjuvant (381), and salvage radiotherapy (454) were analysed.Both systems significantly predicted biochemical-relapse-free-survival, metastasis-free-survival, and disease-free-survival, while only the NCCN system correlated with local-control in the definitive radiotherapy group. In the adjuvant setting, both systems failed to predict all outcomes. In the salvage setting, only the NCCN system significantly predicted biochemical-relapse-free-survival, metastasis-free-survival and disease-free-survival.This analysis confirms the efficacy of both systems in definitive radiotherapy and suggests the utility of the NCCN also in salvage radiotherapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1f4edcc237f13f0021c85e9ebf2082f9 https://pubmed.ncbi.nlm.nih.gov/32727771 Zobrazit plný text záznamu