[MLPA technique--principles and use in practice]

Autor:	Cristina, Rusu, Adriana, Sireteanu, Maria, Puiu, Cristina, Skrypnyk, E, Tomescu, Katalin, Csep, Victoria, Creţ, Ligia, Barbarii
Jazyk:	Romanian; Moldavian; Moldovan
Rok vydání:	2008
Předmět:	Gene Rearrangement Gene Duplication Cytogenetic Analysis Humans Reproducibility of Results Genetic Testing DNA Methylation Aneuploidy Nucleic Acid Amplification Techniques Polymerase Chain Reaction Gene Deletion
Zdroj:	Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 111(4)
ISSN:	0048-7848
Popis:	MLPA (Multiplex Ligation-dependent Probe Amplification) is a recently introduced method, based on PCR principle, useful for the detection of different genetic abnormalities (aneuploidies, gene deletions/duplications, subtelomeric rearrangements, methylation status etc). The technique is simple, reliable and cheap. We present this method to discuss its importance for a modern genetic service and to underline its multiple advantages.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1f2d1f721339fc912e7b3c16a5ed7401 https://pubmed.ncbi.nlm.nih.gov/18389795 Zobrazit plný text záznamu