[Surveillance of falciparum malaria susceptibility to antimalarial drugs and policy change in the Comoros]
| Autor: | R, Silai, M, Moussa, M, Abdalli Mari, M, Astafieva-Djaza, M, Hafidhou, A, Oumadi, M, Randrianarivelojosia, A, Said Ankili, B, Said Ahmed, A H, Gayibor, F, Ariey, P, Ringwald |
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| Jazyk: | francouzština |
| Rok vydání: | 2007 |
| Předmět: |
Male
Genotype Consensus Development Conferences as Topic Plasmodium falciparum Drug Resistance World Health Organization Comoros Antimalarials Clinical Protocols Recurrence Animals Humans Malaria Falciparum Child Fluorenes Lumefantrine Health Policy Infant Chloroquine Artemisinins Drug Combinations Ethanolamines Child Preschool Practice Guidelines as Topic Female Artemether Public Health Administration |
| Zdroj: | Bulletin de la Societe de pathologie exotique (1990). 100(1) |
| ISSN: | 0037-9085 |
| Popis: | Between May and June 2001, efficacy of chloroquine was assessed in 5 sentinel sites in the 3 Comoro islands. Among the 183 children, age range between 6 and 59 months, followed up for 14 days, clinical failure rates ranged between 31.2 and 73.1% and the total failure rate (clinical and parasitological) between 50 and 88.5%. Failures were mainly early treatment failures. The Ministry of health, during a consensus meeting decided to change the first line drug and to gather baseline information on the efficacy and the tolerance of the combination artemether-lumefantrine. Between June and September 2004, among the 164 children, age range between 6 and 59 months included, the success rate of the combination was 99.4% in the 3 sites with a follow-up of 28 days. No serious drug related adverse event was reported. |
| Databáze: | OpenAIRE |
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