[The effect of mutation him1 characterized by enhanced induced mutagenesis on the genetic effects of 6-N-hydroxylaminopurine in Saccharomyces cerevisiae]

Autor:	E L, Ivanov, S N, Sadykov, I K, Koroleva
Rok vydání:	1990
Předmět:	Adenine Genes Fungal Mutation Saccharomyces cerevisiae Mutagens
Zdroj:	Genetika. 26(1)
ISSN:	0016-6758
Popis:	The him1 mutation has been shown to influence the genetic effects of the mutagenic purine base analog 6-hydroxylaminopurine, i. e. inactivation of haploid cells, mutation induction, and inhibition of DNA synthesis in vivo. The influence observed is well consistent with the idea that the him1 mutation affects mismatch correction. We present evidence that during in vivo DNA replication 6-hydroxylaminopurine incorporates into the yeast DNA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1e2cf9ed35ecf695852d4c3f6d505479 https://pubmed.ncbi.nlm.nih.gov/2188875 Zobrazit plný text záznamu