Double-blind placebo-controlled trial of quetiapine in anorexia nervosa

Autor:	Pauline S, Powers, Megan, Klabunde, Walter, Kaye
Rok vydání:	2012
Předmět:	Adult Male Psychiatric Status Rating Scales Dibenzothiazepines Quetiapine Fumarate Anorexia Nervosa Double-Blind Method Surveys and Questionnaires Humans Female Article Antipsychotic Agents
Zdroj:	European eating disorders review : the journal of the Eating Disorders Association. 20(4)
ISSN:	1099-0968
Popis:	Our objective is to determine whether quetiapine was superior to placebo in increasing weight or reducing core symptoms of anorexia nervosa as assessed by the Yale-Brown-Cornell Eating Disorder Scale and the Eating Disorder Inventory-2.Participants were randomised to 8 weeks of quetiapine or placebo.There are 21 participants who signed informed consent, 15 were randomised, 14 returned for at least one visit after receiving drug and 10 completed the study. There were no differences between drug and placebo in questionnaire scores, weight or measures of anxiety or depression.There was no difference between quetiapine and placebo on weight gain or core symptoms. Small effect sizes suggest that a higher number of participants would not increase significant differences between groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1e23b8c37849de98f5a741211d4d5207 https://pubmed.ncbi.nlm.nih.gov/22535517 Zobrazit plný text záznamu Plný text