Reversal by indomethacin of renal effects of dopamine in subjects with normal renal function

Autor:	N L, Yeyati, G A, Altenberg, F A, Rainoldi, J, Greco
Rok vydání:	1986
Předmět:	Adult Indomethacin Dopamine Antagonists Humans Middle Aged Water-Electrolyte Balance Kidney Glomerular Filtration Rate
Zdroj:	Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia. 36(2)
ISSN:	0326-6656
Popis:	In five subjects with normal renal function, intravenous dopamine, at a rate of 6 ug/kg/min, produces a renal vasodilation, increase in Na excretion and reduction in urinary osmolality, without modification in glomerular filtration rate. These effects were reversed by intravenous indomethacin (2 mg/kg), suggesting that the renal effects of dopamine might depend on normal prostaglandins production.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1df7b09e6a44f499d4f0d8e40557fe96 https://pubmed.ncbi.nlm.nih.gov/2950721 Zobrazit plný text záznamu