| Autor: |
Hiromitsu, Sugawara, Masataka, Ichiki, Keijyou, Sai, Keisuke, Kamata, Makoto, Ansai, Yoshiyuki, Nakano, Masashi, Kawamura, Azusa, Ichinose, Shukichi, Miyazaki |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 36(5) |
| ISSN: |
0385-0684 |
| Popis: |
We have recently experienced a case in which S-1/CDDP combination therapy proved remarkably efficacious for a rapid, extensive lymph node recurrence with metastasis into a Virchow node that had developed after resection of advanced gastric carcinoma accompanied with a marked invasion of the esophagus. The patient, a woman aged 73, underwent a total gastrectomy upon left thoracolaparotomy for a gastric carcinoma at the cardia with a 5-cm involvement of the esophagus. On day 65 post-operation, a diagnosis of Virchow node and para-aortic lymph node recurrence was made on the basis of CT scan findings. Of tumor markers checked, CEA and CA19-9 were noted to be increased to as high as 37.55 ng/mL and 3,235 U/mL, respectively. The patient received three courses of S-1/CDDP combination therapy, with a consequent noticeable contraction of the Virchow node and enlarged para-aortic lymph node. Further, she was given two courses of S-1 therapy, which resulted in normalization of tumor markers. The patient has since been on continued chemotherapy without any sign of recurrence. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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