[Modification of cytochrome P-450 apoenzyme during its oxidative self-inactivation in a reconstituted mono-oxygenase system]

Autor:	V G, Zgoda, I I, Karuzina, O V, Nikitiuk, A I, Archakov
Rok vydání:	1996
Předmět:	Molecular Weight Protein Denaturation Apoenzymes Spectrometry Fluorescence Steroid Hydroxylases Cytochrome P-450 Enzyme Inhibitors Aryl Hydrocarbon Hydroxylases Chromatography Ion Exchange Oxidation-Reduction Chromatography High Pressure Liquid
Zdroj:	Voprosy meditsinskoi khimii. 42(3)
ISSN:	0042-8809
Popis:	The hemoprotein self-inactivation is accompanied by oxidation of all-groups, carbonyl group formation, changes in aggregate state and apoenzyme polymerization. It is probable that heme loss and oxidative modification of apoenzyme is a important step in regulation of P450 decay in cell.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1d55e5ab9894c8ccee70e19e30b91ea9 https://pubmed.ncbi.nlm.nih.gov/9139451 Zobrazit plný text záznamu