Therapy-related refractory anemia with ringed sideroblasts in chronic lymphocytic leukemia. involvement of 3q21 region

Autor:	M, Yağci, G T, Sucak, G, Oğur, R, Haznedar
Rok vydání:	2001
Předmět:	Chromosome Aberrations Leukemia Myeloid Acute Anemia Refractory Humans Female Neoplasms Second Primary Chromosomes Human Pair 3 Middle Aged Leukemia Lymphocytic Chronic B-Cell
Zdroj:	Cancer genetics and cytogenetics. 129(1)
ISSN:	0165-4608
Popis:	Therapy-related myelodysplastic syndrome/acute myelogenous leukemia (t-MDS/AML) is extremely rare in chronic lymphocytic leukemia (CLL) despite extensive use of alkylating agents. We present a case of heavily treated CLL with resultant therapy-related refractory anemia with ringed sideroblasts (RARS). A complex cytogenetic abnormality including involvement of 3q21 was detected and to our knowledge, is the first report of a RARS case with a 3q21 abnormality.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1ce458340ae4f5a10d436d53c0b9a111 https://pubmed.ncbi.nlm.nih.gov/11520565 Zobrazit plný text záznamu Full Text from ScienceDirect