Use of the Fourier series window protocol with a zig-zag surface coil in 31P NMR human skin spectroscopy. A theoretical study

Autor:	M E, Bastin, A G, Cowie, D N, Manners, L J, Hands, P, Styles
Rok vydání:	1996
Předmět:	Magnetic Resonance Spectroscopy Fourier Analysis Humans Reproducibility of Results Phosphorus Muscle Skeletal Mathematical Computing Skin
Zdroj:	NMR in biomedicine. 9(5)
ISSN:	0952-3480
Popis:	The use of a zig-zag surface coil with a three-pulse Fourier Series Window (FSW) has been suggested as a means by which in vivo NMR spectroscopic studies of human skin can be performed. Using direct numerical simulations of the magnetic field profile of a 10 limb zig-zag surface coil, the role of the FSW in reducing NMR signals originating from the deeper skeletal muscle layers is examined theoretically. The extent of muscle signal contamination is determined for different coil inter-limb spacings and pulse width settings. The optimum inter-limb spacing for studying living human skin, that which minimizes signal contamination and maximizes skin signal collected, is shown to be between 4 and 6 mm. These calculations demonstrate that the FSW and zig-zag surface coil offer a protocol for investigating the metabolism of large areas of surface tissue while keeping signal contamination from the deeper skeletal muscle layers down to an acceptable level.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1ccd9aa58f70903f09bf8c4ac0d65667 https://pubmed.ncbi.nlm.nih.gov/9068001 Zobrazit plný text záznamu Plný text