[Effect of a purine-free diet on the purine phosphoribosyltransferase activity of erythrocytes in patients with Lesch-Nyhan syndrome]

Autor:	I A, Semenova, N P, Pen'kovskaia
Rok vydání:	1984
Předmět:	Male Hypoxanthine Phosphoribosyltransferase Erythrocytes Adolescent Lesch-Nyhan Syndrome Purines Child Preschool Adenine Phosphoribosyltransferase Humans Pentosyltransferases Child Diet
Zdroj:	Voprosy meditsinskoi khimii. 30(4)
ISSN:	0042-8809
Popis:	Activity of purine phosphoribosyl transferases was studied in 11 patients with Lesch-Nyhan syndrome before and within 1 or 3 months after beginning of the purine-free diet treatment. The enzymatic activity tended to normalization within 1 month after the dietary treatment but the ratio of the enzymes activity was deteriorated within the subsequent 3 months of treatment. A positive clinical effect of the purine-free diet was noted.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::1cc1f6c2e77548bb885d17a1a1d4ba82 https://pubmed.ncbi.nlm.nih.gov/6506590 Zobrazit plný text záznamu