| Autor: |
T, Krupin, G W, Webb, A T, Barbosa, B, Gulli, J, Levine, B, Becker |
| Rok vydání: |
1984 |
| Předmět: |
|
| Zdroj: |
Investigative ophthalmologyvisual science. 25(8) |
| ISSN: |
0146-0404 |
| Popis: |
Administration of either thyrotropin-releasing hormone (TRH) or arginine vasopressin (a-VP) into the rabbit third ventricle elevated intraocular pressure (IOP). IOP was increased 3.6 mmHg 45 min after TRH (10 ng/0.1 ml) administration and increased 6.4 mmHg 45 min following delivery of a-VP (5 micrograms/0.1 ml). Outflow facility and episcleral venous pressure were not altered by either agent. Estimated aqueous humor flow 45 min after third ventricle administration was increased 66% after TRH and 91% after a-VP delivery. Posterior chamber aqueous humor ascorbate was reduced 60 min after TRH administration. Pretreatment with either systemic or topical atropine prevented the TRH or a-VP induced increase in IOP. Body temperature (BT), which was unaltered after TRH administration, was elevated by third ventricle delivery of a-VP. The a-VP induced increase in BT was blocked by systemic pretreatment with either indomethacin or atropine. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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